ABSTRACT
Intramuscular lipoma of the chest wall is a rare finding. We present the case of a 51years male who presented to the hospital with mass on the left side of the chest which was gradually progressive in size. After re- evaluation swelling was round in shape, single with well-defined margin and rubbery consistency. Preoperative imaging HRCT thorax was done which suggested a well-defined round, hypodense, non-enhancing space occupying lesion (10.2x 8.6 x2.3cm) with volume of approximately 100ml noted in the muscle of the chest wall (pectoralis major to pectoralis minor) in the left side of the chest most likely lipoma. Histopathology revealed normal adipocytes with small eccentric nucleus.
ABSTRACT
Background: Diabetic nephropathy (DN) is a chronic complication of diabetes mellitus with a growing incidence. Therefore, it is essential to have a better understanding of it, especially in relation to prevention and aggressive management to avoid progression to end-stage renal disease. Methods: This prospective randomized study represented the effects of ramipril on glycosylated hemoglobin (HbA1c), liver function tests (LFT), mean arterial blood pressure, and serum potassium level in patients diagnosed with DN, with concomitant mild to moderate hypertension. 135 diagnosed patients with DN treated with ramipril 5 mg daily for 3 months were involved in this study. Blood samples were taken from all patients and analyzed for HbA1c, LFT including alanine aminotransferase (ALT), aspartate aminotransferase (AST), serum alkaline phosphatase (ALP), and bilirubin with serum potassium level. After 3 months of treatment with ramipril (5 mg daily), blood samples were collected and analyzed again to determine the same parameters. Results: Ramipril produced a signifi cant reduction in (HbA1c) of hypertensive patients (p<0.05), whereas, serum levels of ALT, AST, ALP, and bilirubin were signifi cantly elevated. The results indicated that ramipril may cause liver injury. Meanwhile, the mean arterial pressure was decreased signifi cantly by ramipril (p<0.05). Conclusion: The present study concluded that: ramipril signifi cantly reduced the percentage of HbA1c but may cause liver injury, monitoring of liver enzymes is advisable for patients on ramipril.
ABSTRACT
Anxiety disorders are more prevalent not only in normal individuals but also in diabetes mellitus. Diazepam, a benzodiazepine, and buspirone, an azaspirodecanedione, are the most often prescribed anxiolytics. Present study was aimed to investigate the effect of diazepam and buspirone on the blood sugar levels in rabbits. Buspirone (0.5 mg/kg/day p.o.) and diazepam (0.6 mg/kg/day p.o.) did not affect the glucose levels in rabbits even after one month of treatment. Present findings suggest that these two anxiolytics have minimal effect on blood sugar control.